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Awesome article! However, I would like to note that Ron Milo and co-authors work was only able to computationally analyze the ~33k Rubisco homologs. They were not able to test all of the retrieved homologs ( ~33k) in a test tube; however, they did purify and experimentally test ~140 sequences.

Overall, I really enjoyed the article and thanks for sharing it!

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First hyperlink under "Future Nightmares" isn't working.

Fascinating read. I strongly dislike pesticides (like glyphosate) as a consumer wary of pollutants that contaminate food like bioaccumulation of PFAS. To most researchers, I acknowledge that I seem exceedingly cautious. Is it accurate to say that concerns over pesticide use should have no bearing on attitudes over "hacking photosynthesis?" It seems like the advantage here is being able to increase biomass yield without resorting to slathering mutagens on crops. Although, I do reserve slight concern over the implications of the innovations discussed here on nutritional yield (e.g do the new plants really have the same amount of protein/other nutrients; do the new modifications not impact how plants absorb nutrients in any significant way?)

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Really interesting-thanks!

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